BDBM50217305 CHEMBL323935

SMILES: NC(=N)c1ccc2oc(cc2c1)C(=O)N1CCN(CC1)C(=O)N1CCN(CC1)C(=O)c1cc2cc(ccc2o1)C(N)=N

InChI Key: InChIKey=ZTIRJAXNXYBOIK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217305   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tryptase (Homo sapiens (Human))	BDBM50217305 (CHEMBL323935) Show SMILES NC(=N)c1ccc2oc(cc2c1)C(=O)N1CCN(CC1)C(=O)N1CCN(CC1)C(=O)c1cc2cc(ccc2o1)C(N)=N Show InChI InChI=1S/C29H30N8O5/c30-25(31)17-1-3-21-19(13-17)15-23(41-21)27(38)34-5-9-36(10-6-34)29(40)37-11-7-35(8-12-37)28(39)24-16-20-14-18(26(32)33)2-4-22(20)42-24/h1-4,13-16H,5-12H2,(H3,30,31)(H3,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yoshitomi Pharmaceutical Industries, LTD. Curated by ChEMBL					Assay Description Inhibition of tryptase activity				Bioorg Med Chem Lett 9: 3285-90 (2000) BindingDB Entry DOI: 10.7270/Q2TX3DK3
					More data for this Ligand-Target Pair