BDBM50217349 4-(6-amino-5-((2-morpholino-2-oxoethoxyimino)methyl)pyrimidin-4-yl)-N-(4-(pyrrolidin-1-yl)phenyl)piperazine-1-carboxamide::CHEMBL391684

SMILES: Nc1ncnc(N2CCN(CC2)C(=O)Nc2ccc(cc2)N2CCCC2)c1\C=N\OCC(=O)N1CCOCC1

InChI Key: InChIKey=VVSRSDHTOYITSP-OCSSWDANSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50217349 (4-(6-amino-5-((2-morpholino-2-oxoethoxyimino)methy...) Show SMILES Nc1ncnc(N2CCN(CC2)C(=O)Nc2ccc(cc2)N2CCCC2)c1\C=N\OCC(=O)N1CCOCC1 Show InChI InChI=1S/C26H35N9O4/c27-24-22(17-30-39-18-23(36)33-13-15-38-16-14-33)25(29-19-28-24)34-9-11-35(12-10-34)26(37)31-20-3-5-21(6-4-20)32-7-1-2-8-32/h3-6,17,19H,1-2,7-16,18H2,(H,31,37)(H2,27,28,29)/b30-17+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Inhibition of human FLT3				Bioorg Med Chem Lett 17: 4861-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.046 BindingDB Entry DOI: 10.7270/Q2T72H47
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