BDBM50217364 4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)-N-(4-chlorophenyl)piperazine-1-carboxamide::CHEMBL235007

SMILES: CO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=HFMBFDASNGVZOF-LSHDLFTRSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50217364 (4-(6-amino-5-((methoxyimino)methyl)pyrimidin-4-yl)...) Show SMILES CO\N=C\c1c(N)ncnc1N1CCN(CC1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C17H20ClN7O2/c1-27-22-10-14-15(19)20-11-21-16(14)24-6-8-25(9-7-24)17(26)23-13-4-2-12(18)3-5-13/h2-5,10-11H,6-9H2,1H3,(H,23,26)(H2,19,20,21)/b22-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development LLC Curated by ChEMBL					Assay Description Inhibition of human FLT3				Bioorg Med Chem Lett 17: 4861-5 (2007) Article DOI: 10.1016/j.bmcl.2007.06.046 BindingDB Entry DOI: 10.7270/Q2T72H47
					More data for this Ligand-Target Pair