BDBM50217378 CHEMBL390987::N-propyl-5-(1H-pyrrol-2-yl)-3-p-tolyl-4,5-dihydropyrazole-1-carbothioamide

SMILES: CCCNC(=S)N1N=C(CC1c1ccc[nH]1)c1ccc(C)cc1

InChI Key: InChIKey=PFSGEFFUKDWKEA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217378   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoamine oxidase (Rattus norvegicus (rat))	BDBM50217378 (CHEMBL390987 | N-propyl-5-(1H-pyrrol-2-yl)-3-p-tol...) Show SMILES CCCNC(=S)N1N=C(CC1c1ccc[nH]1)c1ccc(C)cc1 |c:7| Show InChI InChI=1S/C18H22N4S/c1-3-10-20-18(23)22-17(15-5-4-11-19-15)12-16(21-22)14-8-6-13(2)7-9-14/h4-9,11,17,19H,3,10,12H2,1-2H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.69E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of rat liver MAOA after 60 mins pre-incubation				Bioorg Med Chem 15: 5775-86 (2007) Article DOI: 10.1016/j.bmc.2007.06.004 BindingDB Entry DOI: 10.7270/Q2JH3N0R
					More data for this Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B) (Rattus norvegicus (rat))	BDBM50217378 (CHEMBL390987 | N-propyl-5-(1H-pyrrol-2-yl)-3-p-tol...) Show SMILES CCCNC(=S)N1N=C(CC1c1ccc[nH]1)c1ccc(C)cc1 |c:7| Show InChI InChI=1S/C18H22N4S/c1-3-10-20-18(23)22-17(15-5-4-11-19-15)12-16(21-22)14-8-6-13(2)7-9-14/h4-9,11,17,19H,3,10,12H2,1-2H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.89E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hacettepe University Curated by ChEMBL					Assay Description Inhibition of rat liver MAOB after 60 mins pre-incubation				Bioorg Med Chem 15: 5775-86 (2007) Article DOI: 10.1016/j.bmc.2007.06.004 BindingDB Entry DOI: 10.7270/Q2JH3N0R
					More data for this Ligand-Target Pair