BDBM50217492 CHEMBL238203::N-(1-isopropyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-4-(2-oxo-1,2-dihydroquinazolin-3(4H)-yl)piperidine-1-carboxamide

SMILES: CC(C)N1c2ccccc2CCC(NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O

InChI Key: InChIKey=LFTGCGDWACHEGE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217492   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217492 (CHEMBL238203 | N-(1-isopropyl-2-oxo-2,3,4,5-tetrah...) Show SMILES CC(C)N1c2ccccc2CCC(NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O Show InChI InChI=1S/C27H33N5O3/c1-18(2)32-24-10-6-4-7-19(24)11-12-23(25(32)33)29-26(34)30-15-13-21(14-16-30)31-17-20-8-3-5-9-22(20)28-27(31)35/h3-10,18,21,23H,11-17H2,1-2H3,(H,28,35)(H,29,34)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [125I]CGRP from human CL receptor in RAMP1 membranes				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1 (Homo sapiens (Human))	BDBM50217492 (CHEMBL238203 | N-(1-isopropyl-2-oxo-2,3,4,5-tetrah...) Show SMILES CC(C)N1c2ccccc2CCC(NC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)C1=O Show InChI InChI=1S/C27H33N5O3/c1-18(2)32-24-10-6-4-7-19(24)11-12-23(25(32)33)29-26(34)30-15-13-21(14-16-30)31-17-20-8-3-5-9-22(20)28-27(31)35/h3-10,18,21,23H,11-17H2,1-2H3,(H,28,35)(H,29,34)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Antagonist activity at human CGRP receptor in E10 cells assessed as inhibition of cAMP production				Bioorg Med Chem Lett 17: 4795-8 (2007) Article DOI: 10.1016/j.bmcl.2007.06.062 BindingDB Entry DOI: 10.7270/Q2JS9Q4D
					More data for this Ligand-Target Pair