BDBM50217720 CHEMBL393755::N-(3-aminopropyl)-2-(1H-indol-3-yl)-N-(1,2,3,4-tetrahydronaphthalen-2-yl)acetamide

SMILES: NCCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12

InChI Key: InChIKey=UCCNNHFPGHICIT-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217720   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 1 (Mus musculus)	BDBM50217720 (CHEMBL393755 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...) Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12 |w:5.4| Show InChI InChI=1S/C23H27N3O/c24-12-5-13-26(20-11-10-17-6-1-2-7-18(17)14-20)23(27)15-19-16-25-22-9-4-3-8-21(19)22/h1-4,6-9,16,20,25H,5,10-15,24H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 5 (MC5R) (Homo sapiens (Human))	BDBM50217720 (CHEMBL393755 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...) Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12 |w:5.4| Show InChI InChI=1S/C23H27N3O/c24-12-5-13-26(20-11-10-17-6-1-2-7-18(17)14-20)23(27)15-19-16-25-22-9-4-3-8-21(19)22/h1-4,6-9,16,20,25H,5,10-15,24H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50217720 (CHEMBL393755 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...) Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12 |w:5.4| Show InChI InChI=1S/C23H27N3O/c24-12-5-13-26(20-11-10-17-6-1-2-7-18(17)14-20)23(27)15-19-16-25-22-9-4-3-8-21(19)22/h1-4,6-9,16,20,25H,5,10-15,24H2	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair
Melanocortin receptor 3 (Homo sapiens (Human))	BDBM50217720 (CHEMBL393755 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...) Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12 |w:5.4| Show InChI InChI=1S/C23H27N3O/c24-12-5-13-26(20-11-10-17-6-1-2-7-18(17)14-20)23(27)15-19-16-25-22-9-4-3-8-21(19)22/h1-4,6-9,16,20,25H,5,10-15,24H2	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells				Bioorg Med Chem 15: 5787-810 (2007) Article DOI: 10.1016/j.bmc.2007.06.003 BindingDB Entry DOI: 10.7270/Q2X066Q5
					More data for this Ligand-Target Pair