BDBM50217904 3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-yl-1H-pyrrolo[2,3-b]pyridine::CHEMBL394233

SMILES: Clc1ccc(CS(=O)(=O)c2cn(C3CCNC3)c3ncccc23)s1

InChI Key: InChIKey=VZQAAXLQPHFJEF-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217904 (3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-y...) Show SMILES Clc1ccc(CS(=O)(=O)c2cn(C3CCNC3)c3ncccc23)s1 |w:12.11| Show InChI InChI=1S/C16H16ClN3O2S2/c17-15-4-3-12(23-15)10-24(21,22)14-9-20(11-5-7-18-8-11)16-13(14)2-1-6-19-16/h1-4,6,9,11,18H,5,7-8,10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217904 (3-(5-chloro-thiophene-2-sulfonyl)-1-pyrrolidin-3-y...) Show SMILES Clc1ccc(CS(=O)(=O)c2cn(C3CCNC3)c3ncccc23)s1 |w:12.11| Show InChI InChI=1S/C16H16ClN3O2S2/c17-15-4-3-12(23-15)10-24(21,22)14-9-20(11-5-7-18-8-11)16-13(14)2-1-6-19-16/h1-4,6,9,11,18H,5,7-8,10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair