null

SMILES: CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1

InChI Key: InChIKey=OAINFPLVHRTSJH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217929   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217929 (3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...) Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1 |w:7.9| Show InChI InChI=1S/C21H24BrN3O2S/c1-15(2)24-11-5-7-17(13-24)25-14-20(19-9-4-10-23-21(19)25)28(26,27)18-8-3-6-16(22)12-18/h3-4,6,8-10,12,14-15,17H,5,7,11,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Binding affinity to 5HT6 receptor				Eur J Med Chem 45: 3911-5 (2010) Article DOI: 10.1016/j.ejmech.2010.05.045 BindingDB Entry DOI: 10.7270/Q27945XK
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217929 (3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...) Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1 |w:7.9| Show InChI InChI=1S/C21H24BrN3O2S/c1-15(2)24-11-5-7-17(13-24)25-14-20(19-9-4-10-23-21(19)25)28(26,27)18-8-3-6-16(22)12-18/h3-4,6,8-10,12,14-15,17H,5,7,11,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cells				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50217929 (3-[(3-bromophenyl)sulfonyl]-1-(1-isopropylpiperidi...) Show SMILES CC(C)N1CCCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1cccc(Br)c1 |w:7.9| Show InChI InChI=1S/C21H24BrN3O2S/c1-15(2)24-11-5-7-17(13-24)25-14-20(19-9-4-10-23-21(19)25)28(26,27)18-8-3-6-16(22)12-18/h3-4,6,8-10,12,14-15,17H,5,7,11,13H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	492	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassay				Bioorg Med Chem 15: 6208-26 (2007) Article DOI: 10.1016/j.bmc.2007.06.024 BindingDB Entry DOI: 10.7270/Q2HT2P2G
					More data for this Ligand-Target Pair