BDBM50217966 CHEMBL54775

SMILES: Cc1ccc2N(CCc2c1Br)C(=O)Nc1ccc(Oc2cccnc2C)nc1

InChI Key: InChIKey=PJGZNSFVSRGOBA-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50217966 (CHEMBL54775) Show SMILES Cc1ccc2N(CCc2c1Br)C(=O)Nc1ccc(Oc2cccnc2C)nc1 Show InChI InChI=1S/C21H19BrN4O2/c1-13-5-7-17-16(20(13)22)9-11-26(17)21(27)25-15-6-8-19(24-12-15)28-18-4-3-10-23-14(18)2/h3-8,10,12H,9,11H2,1-2H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50217966 (CHEMBL54775) Show SMILES Cc1ccc2N(CCc2c1Br)C(=O)Nc1ccc(Oc2cccnc2C)nc1 Show InChI InChI=1S/C21H19BrN4O2/c1-13-5-7-17-16(20(13)22)9-11-26(17)21(27)25-15-6-8-19(24-12-15)28-18-4-3-10-23-14(18)2/h3-8,10,12H,9,11H2,1-2H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50217966 (CHEMBL54775) Show SMILES Cc1ccc2N(CCc2c1Br)C(=O)Nc1ccc(Oc2cccnc2C)nc1 Show InChI InChI=1S/C21H19BrN4O2/c1-13-5-7-17-16(20(13)22)9-11-26(17)21(27)25-15-6-8-19(24-12-15)28-18-4-3-10-23-14(18)2/h3-8,10,12H,9,11H2,1-2H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserin				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair