BDBM50217983 CHEMBL53113

SMILES: Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)nc3)c2cc1Cl

InChI Key: InChIKey=RVJAKPBOJZUTJG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217983   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50217983 (CHEMBL53113) Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)nc3)c2cc1Cl Show InChI InChI=1S/C20H18ClN5O2/c1-12-8-14-5-7-26(17(14)9-16(12)21)20(27)25-15-10-23-19(24-11-15)28-18-4-3-6-22-13(18)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50217983 (CHEMBL53113) Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)nc3)c2cc1Cl Show InChI InChI=1S/C20H18ClN5O2/c1-12-8-14-5-7-26(17(14)9-16(12)21)20(27)25-15-10-23-19(24-11-15)28-18-4-3-6-22-13(18)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50217983 (CHEMBL53113) Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)nc3)c2cc1Cl Show InChI InChI=1S/C20H18ClN5O2/c1-12-8-14-5-7-26(17(14)9-16(12)21)20(27)25-15-10-23-19(24-11-15)28-18-4-3-6-22-13(18)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserin				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair