BDBM50217988 CHEMBL55792

SMILES: CCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1

InChI Key: InChIKey=QBUJZYLJDSBJKB-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217988   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50217988 (CHEMBL55792) Show SMILES CCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1 Show InChI InChI=1S/C22H21ClN4O2/c1-3-18-20(5-4-9-24-18)29-21-7-6-16(13-25-21)26-22(28)27-10-8-15-11-14(2)17(23)12-19(15)27/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50217988 (CHEMBL55792) Show SMILES CCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1 Show InChI InChI=1S/C22H21ClN4O2/c1-3-18-20(5-4-9-24-18)29-21-7-6-16(13-25-21)26-22(28)27-10-8-15-11-14(2)17(23)12-19(15)27/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,26,28)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50217988 (CHEMBL55792) Show SMILES CCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1 Show InChI InChI=1S/C22H21ClN4O2/c1-3-18-20(5-4-9-24-18)29-21-7-6-16(13-25-21)26-22(28)27-10-8-15-11-14(2)17(23)12-19(15)27/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserin				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair