BDBM50217993 CHEMBL55292

SMILES: Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c4CCOc4c(cc23)C(F)(F)F)cn1

InChI Key: InChIKey=HVFIZGFUTYQRCG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50217993 (CHEMBL55292) Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c4CCOc4c(cc23)C(F)(F)F)cn1 Show InChI InChI=1S/C23H19F3N4O3/c1-13-19(3-2-8-27-13)33-20-5-4-14(12-28-20)29-22(31)30-9-6-15-16-7-10-32-21(16)17(11-18(15)30)23(24,25)26/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50217993 (CHEMBL55292) Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c4CCOc4c(cc23)C(F)(F)F)cn1 Show InChI InChI=1S/C23H19F3N4O3/c1-13-19(3-2-8-27-13)33-20-5-4-14(12-28-20)29-22(31)30-9-6-15-16-7-10-32-21(16)17(11-18(15)30)23(24,25)26/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50217993 (CHEMBL55292) Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c4CCOc4c(cc23)C(F)(F)F)cn1 Show InChI InChI=1S/C23H19F3N4O3/c1-13-19(3-2-8-27-13)33-20-5-4-14(12-28-20)29-22(31)30-9-6-15-16-7-10-32-21(16)17(11-18(15)30)23(24,25)26/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserin				Bioorg Med Chem Lett 10: 1863-6 (2000) BindingDB Entry DOI: 10.7270/Q2X63Q4P
					More data for this Ligand-Target Pair