BDBM50218090 (4-(2-((1H-pyrazol-1-yl)methyl)phenyl)piperazin-1-yl)((3S,4R)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-3-yl)methanone::CHEMBL400595

SMILES: CC(C)N1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1Cn1cccn1

InChI Key: InChIKey=XYEZUYUICZOZJH-IZZNHLLZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50218090 ((4-(2-((1H-pyrazol-1-yl)methyl)phenyl)piperazin-1-...) Show SMILES CC(C)N1C[C@H]([C@@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)c1ccccc1Cn1cccn1 Show InChI InChI=1S/C28H34ClN5O/c1-21(2)33-19-25(22-8-10-24(29)11-9-22)26(20-33)28(35)32-16-14-31(15-17-32)27-7-4-3-6-23(27)18-34-13-5-12-30-34/h3-13,21,25-26H,14-20H2,1-2H3/t25-,26+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]NDP-MSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 5165-70 (2007) Article DOI: 10.1016/j.bmcl.2007.06.088 BindingDB Entry DOI: 10.7270/Q20R9P37
					More data for this Ligand-Target Pair