BDBM50218184 (R)-N-(5-(2-(4-(2-methylthiazol-4-yl)phenethylamino)-1-hydroxyethyl)-2-chlorophenyl)methanesulfonamide::CHEMBL250385

SMILES: Cc1nc(cs1)-c1ccc(CCNC[C@H](O)c2ccc(Cl)c(NS(C)(=O)=O)c2)cc1

InChI Key: InChIKey=GYBRSFWAQZVMDN-NRFANRHFSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50218184 ((R)-N-(5-(2-(4-(2-methylthiazol-4-yl)phenethylamin...) Show SMILES Cc1nc(cs1)-c1ccc(CCNC[C@H](O)c2ccc(Cl)c(NS(C)(=O)=O)c2)cc1 Show InChI InChI=1S/C21H24ClN3O3S2/c1-14-24-20(13-29-14)16-5-3-15(4-6-16)9-10-23-12-21(26)17-7-8-18(22)19(11-17)25-30(2,27)28/h3-8,11,13,21,23,25-26H,9-10,12H2,1-2H3/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human adrenergic beta-3 receptor expressed in CHO cells assessed as cAMP production				Bioorg Med Chem Lett 17: 5245-50 (2007) Article DOI: 10.1016/j.bmcl.2007.06.072 BindingDB Entry DOI: 10.7270/Q2MK6CMZ
					More data for this Ligand-Target Pair