BDBM50218195 CHEMBL55335

SMILES: Cc1cc2CCN(C(=O)Nc3ccc(OCc4ccccn4)cc3)c2cc1C(F)(F)F

InChI Key: InChIKey=ZSBXYKUYFWLPSO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218195   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50218195 (CHEMBL55335) Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(OCc4ccccn4)cc3)c2cc1C(F)(F)F Show InChI InChI=1S/C23H20F3N3O2/c1-15-12-16-9-11-29(21(16)13-20(15)23(24,25)26)22(30)28-17-5-7-19(8-6-17)31-14-18-4-2-3-10-27-18/h2-8,10,12-13H,9,11,14H2,1H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by [3H]mesulergine displacement.				Bioorg Med Chem Lett 10: 1867-70 (2000) BindingDB Entry DOI: 10.7270/Q2SF2ZB2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50218195 (CHEMBL55335) Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(OCc4ccccn4)cc3)c2cc1C(F)(F)F Show InChI InChI=1S/C23H20F3N3O2/c1-15-12-16-9-11-29(21(16)13-20(15)23(24,25)26)22(30)28-17-5-7-19(8-6-17)31-14-18-4-2-3-10-27-18/h2-8,10,12-13H,9,11,14H2,1H3,(H,28,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned 5-hydroxytryptamine 2B receptor of HEK293 cells by [3H]5-HT displacement.				Bioorg Med Chem Lett 10: 1867-70 (2000) BindingDB Entry DOI: 10.7270/Q2SF2ZB2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50218195 (CHEMBL55335) Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(OCc4ccccn4)cc3)c2cc1C(F)(F)F Show InChI InChI=1S/C23H20F3N3O2/c1-15-12-16-9-11-29(21(16)13-20(15)23(24,25)26)22(30)28-17-5-7-19(8-6-17)31-14-18-4-2-3-10-27-18/h2-8,10,12-13H,9,11,14H2,1H3,(H,28,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	398	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description In vitro binding affinity at human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by [3H]ketanserin displacement.				Bioorg Med Chem Lett 10: 1867-70 (2000) BindingDB Entry DOI: 10.7270/Q2SF2ZB2
					More data for this Ligand-Target Pair