BDBM50218270 (Z)-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methylthiazol-2(3H)-ylidene)naphthalene-1-sulfonamide::CHEMBL236374
SMILES: Cc1c(s\c(=N/S(=O)(=O)c2cccc3ccccc23)n1CC1CC1)C(C)(C)C
InChI Key: InChIKey=OCZGZWPFOZMXFE-LNVKXUELSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50218270 ((Z)-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Agonist activity at human CB2 receptor expressed in CHO cells by [35S]GTPgamaS binding assay | Bioorg Med Chem Lett 17: 5133-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.005 BindingDB Entry DOI: 10.7270/Q27944C0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 2 (Homo sapiens (Human)) | BDBM50218270 ((Z)-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Displacement of [3H] CP-55,940 from human CB2 receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 5133-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.005 BindingDB Entry DOI: 10.7270/Q27944C0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cannabinoid receptor 1 (Homo sapiens (Human)) | BDBM50218270 ((Z)-N-(5-tert-butyl-3-(cyclopropylmethyl)-4-methyl...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL | Assay Description Displacement of [3H] CP-55,940 from human CB1 receptor expressed in CHO cells | Bioorg Med Chem Lett 17: 5133-5 (2007) Article DOI: 10.1016/j.bmcl.2007.07.005 BindingDB Entry DOI: 10.7270/Q27944C0 | |||||||||||
More data for this Ligand-Target Pair |