BDBM50218337 CHEMBL397170::N1-[4-methyl-5-(6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)-2-thienyl]-2-chloroacetamide

SMILES: Cc1cc(NC(=O)CCl)sc1-c1nnc2sc(nn12)-c1ccccc1

InChI Key: InChIKey=UEFVCKVWJQJSDH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50218337 (CHEMBL397170 | N1-[4-methyl-5-(6-phenyl[1,2,4]tria...) Show SMILES Cc1cc(NC(=O)CCl)sc1-c1nnc2sc(nn12)-c1ccccc1 Show InChI InChI=1S/C16H12ClN5OS2/c1-9-7-12(18-11(23)8-17)24-13(9)14-19-20-16-22(14)21-15(25-16)10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H,18,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Cdk5/p25				Bioorg Med Chem 15: 6397-406 (2007) Article DOI: 10.1016/j.bmc.2007.06.053 BindingDB Entry DOI: 10.7270/Q2JS9RP0
					More data for this Ligand-Target Pair