BDBM50218350 CHEMBL239203::N1-[5-(4-amino-5-sulfanyl-4H-1,2,4-triazol-3-yl)-4-methyl-2-thienyl]acetamide

SMILES: CC(=O)Nc1cc(C)c(s1)-c1n[nH]c(=S)n1N

InChI Key: InChIKey=HONCRTYDCHPQOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50218350 (CHEMBL239203 | N1-[5-(4-amino-5-sulfanyl-4H-1,2,4-...) Show SMILES CC(=O)Nc1cc(C)c(s1)-c1n[nH]c(=S)n1N Show InChI InChI=1S/C9H11N5OS2/c1-4-3-6(11-5(2)15)17-7(4)8-12-13-9(16)14(8)10/h3H,10H2,1-2H3,(H,11,15)(H,13,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Cdk5/p25				Bioorg Med Chem 15: 6397-406 (2007) Article DOI: 10.1016/j.bmc.2007.06.053 BindingDB Entry DOI: 10.7270/Q2JS9RP0
					More data for this Ligand-Target Pair