BDBM50218364 CHEMBL235660::N1-{5-[7-[(Z)-1-(4-chlorophenyl)methylidene]-6-(2,4-dichloro-5-fluorophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]-thiadiazin-3-yl]-4-phenyl-2-thienyl}-2-chloroacetamide

SMILES: Fc1cc(C2=Nn3c(S\C2=C/c2ccc(Cl)cc2)nnc3-c2sc(NC(=O)CCl)cc2-c2ccccc2)c(Cl)cc1Cl

InChI Key: InChIKey=WYVSUBKAMKEZEI-RMORIDSASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 5 activator 1 (Homo sapiens (Human))	BDBM50218364 (CHEMBL235660 | N1-{5-[7-[(Z)-1-(4-chlorophenyl)met...) Show SMILES Fc1cc(C2=Nn3c(S\C2=C/c2ccc(Cl)cc2)nnc3-c2sc(NC(=O)CCl)cc2-c2ccccc2)c(Cl)cc1Cl |t:4| Show InChI InChI=1S/C29H16Cl4FN5OS2/c30-14-24(40)35-25-12-18(16-4-2-1-3-5-16)27(42-25)28-36-37-29-39(28)38-26(19-11-22(34)21(33)13-20(19)32)23(41-29)10-15-6-8-17(31)9-7-15/h1-13H,14H2,(H,35,40)/b23-10-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Cdk5/p25				Bioorg Med Chem 15: 6397-406 (2007) Article DOI: 10.1016/j.bmc.2007.06.053 BindingDB Entry DOI: 10.7270/Q2JS9RP0
					More data for this Ligand-Target Pair