BindingDB logo
myBDB logout

null

SMILES: ClCC(=O)Nc1cc(c(s1)-c1nnc2SCC(=O)Nn12)-c1ccccc1

InChI Key: InChIKey=KIJRIJFRVAOZCO-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218375   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 5 activator 1


(Homo sapiens (Human))		BDBM50218375
PNG
(CHEMBL238116 | N1-[4-phenyl-5-(6-oxo-6,7-dihydro-5...)
Show SMILES ClCC(=O)Nc1cc(c(s1)-c1nnc2SCC(=O)Nn12)-c1ccccc1
Show InChI InChI=1S/C16H12ClN5O2S2/c17-7-11(23)18-13-6-10(9-4-2-1-3-5-9)14(26-13)15-19-20-16-22(15)21-12(24)8-25-16/h1-6H,7-8H2,(H,18,23)(H,21,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 634n/an/an/an/an/an/a



Dr. Reddy's Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against Cdk5/p25

Bioorg Med Chem 15: 6397-406 (2007)


Article DOI: 10.1016/j.bmc.2007.06.053
BindingDB Entry DOI: 10.7270/Q2JS9RP0
More data for this
Ligand-Target Pair