null

SMILES: CN1c2ccc(cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C)S(=O)(=O)Nc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=ZKSXGJLCMGEXQK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218427   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218427 (4-[5,7,7,10,10-pentamethyl-2-(4-trifluoromethoxy-p...) Show SMILES CN1c2ccc(cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C)S(=O)(=O)Nc1ccc(OC(F)(F)F)cc1 |t:9| Show InChI InChI=1S/C36H34F3N3O5S/c1-34(2)16-17-35(3,4)28-20-31-26(19-27(28)34)32(21-6-8-22(9-7-21)33(43)44)40-29-18-25(14-15-30(29)42(31)5)48(45,46)41-23-10-12-24(13-11-23)47-36(37,38)39/h6-15,18-20,41H,16-17H2,1-5H3,(H,43,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of 9-cis-retinoic acid-induced RXRalpha transactivation				Bioorg Med Chem Lett 17: 4804-7 (2007) Article DOI: 10.1016/j.bmcl.2007.06.080 BindingDB Entry DOI: 10.7270/Q2ZS2W7W
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218427 (4-[5,7,7,10,10-pentamethyl-2-(4-trifluoromethoxy-p...) Show SMILES CN1c2ccc(cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C)S(=O)(=O)Nc1ccc(OC(F)(F)F)cc1 |t:9| Show InChI InChI=1S/C36H34F3N3O5S/c1-34(2)16-17-35(3,4)28-20-31-26(19-27(28)34)32(21-6-8-22(9-7-21)33(43)44)40-29-18-25(14-15-30(29)42(31)5)48(45,46)41-23-10-12-24(13-11-23)47-36(37,38)39/h6-15,18-20,41H,16-17H2,1-5H3,(H,43,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Inhibition of LG100268-induced RXRalpha transactivation				Bioorg Med Chem Lett 17: 4804-7 (2007) Article DOI: 10.1016/j.bmcl.2007.06.080 BindingDB Entry DOI: 10.7270/Q2ZS2W7W
					More data for this Ligand-Target Pair