null

SMILES: CCCCS(=O)(=O)Nc1ccc2N(CCC)c3cc4c(cc3C(=Nc2c1)c1ccc(cc1)C(O)=O)C(C)(C)CCC4(C)C

InChI Key: InChIKey=KJHJGOYSQXEGLD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218461 (4-[2-(butane-1-sulfonylamino)-7,7,10,10-tetramethy...) Show SMILES CCCCS(=O)(=O)Nc1ccc2N(CCC)c3cc4c(cc3C(=Nc2c1)c1ccc(cc1)C(O)=O)C(C)(C)CCC4(C)C |c:23| Show InChI InChI=1S/C35H43N3O4S/c1-7-9-19-43(41,42)37-25-14-15-30-29(20-25)36-32(23-10-12-24(13-11-23)33(39)40)26-21-27-28(22-31(26)38(30)18-8-2)35(5,6)17-16-34(27,3)4/h10-15,20-22,37H,7-9,16-19H2,1-6H3,(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of LG100268-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair
Retinoic acid receptor RXR-alpha (Homo sapiens (Human))	BDBM50218461 (4-[2-(butane-1-sulfonylamino)-7,7,10,10-tetramethy...) Show SMILES CCCCS(=O)(=O)Nc1ccc2N(CCC)c3cc4c(cc3C(=Nc2c1)c1ccc(cc1)C(O)=O)C(C)(C)CCC4(C)C |c:23| Show InChI InChI=1S/C35H43N3O4S/c1-7-9-19-43(41,42)37-25-14-15-30-29(20-25)36-32(23-10-12-24(13-11-23)33(39)40)26-21-27-28(22-31(26)38(30)18-8-2)35(5,6)17-16-34(27,3)4/h10-15,20-22,37H,7-9,16-19H2,1-6H3,(H,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of 9-cis-retinoic acid-induced transactivation				Bioorg Med Chem Lett 17: 4808-11 (2007) Article DOI: 10.1016/j.bmcl.2007.06.079 BindingDB Entry DOI: 10.7270/Q2V40TWB
					More data for this Ligand-Target Pair