BDBM50218662 CHEMBL100943

SMILES: CCN(CC)c1nccn2c(Nc3c(C)cc(C)cc3C)nc(CC)c12

InChI Key: InChIKey=DTJRTEVICLKDAG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50218662 (CHEMBL100943) Show SMILES CCN(CC)c1nccn2c(Nc3c(C)cc(C)cc3C)nc(CC)c12 Show InChI InChI=1S/C21H29N5/c1-7-17-19-20(25(8-2)9-3)22-10-11-26(19)21(23-17)24-18-15(5)12-14(4)13-16(18)6/h10-13H,7-9H2,1-6H3,(H,23,24)	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	143	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.				Bioorg Med Chem Lett 12: 291-4 (2002) BindingDB Entry DOI: 10.7270/Q22N54H2
					More data for this Ligand-Target Pair