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BDBM50218669 CHEMBL97868

SMILES: CCN(CC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CC)c12

InChI Key: InChIKey=PTEIQBSXNUWQGF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218669   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50218669
PNG
(CHEMBL97868)
Show SMILES CCN(CC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(CC)c12
Show InChI InChI=1S/C18H21Cl2N5/c1-4-14-16-17(24(5-2)6-3)21-9-10-25(16)18(22-14)23-15-8-7-12(19)11-13(15)20/h7-11H,4-6H2,1-3H3,(H,22,23)
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PubMed
 127n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.

Bioorg Med Chem Lett 12: 291-4 (2002)


BindingDB Entry DOI: 10.7270/Q22N54H2
More data for this
Ligand-Target Pair