BDBM50218680 CHEMBL318652

SMILES: CCN(CC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(C)c12

InChI Key: InChIKey=ARFPVRNQRQPFFW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218680   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor (Rattus norvegicus (rat)-RAT)	BDBM50218680 (CHEMBL318652) Show SMILES CCN(CC)c1nccn2c(Nc3ccc(Cl)cc3Cl)nc(C)c12 Show InChI InChI=1S/C17H19Cl2N5/c1-4-23(5-2)16-15-11(3)21-17(24(15)9-8-20-16)22-14-7-6-12(18)10-13(14)19/h6-10H,4-5H2,1-3H3,(H,21,22)	PDB MMDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	485	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.				Bioorg Med Chem Lett 12: 291-4 (2002) BindingDB Entry DOI: 10.7270/Q22N54H2
					More data for this Ligand-Target Pair