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BDBM50218683 CHEMBL98643

SMILES: CCCc1nc(N(C)c2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12

InChI Key: InChIKey=FKNDDPQLOWCCCD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218683   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50218683
PNG
(CHEMBL98643)
Show SMILES CCCc1nc(N(C)c2ccc(Cl)cc2Cl)n2ccnc(N(CC)CC)c12
Show InChI InChI=1S/C20H25Cl2N5/c1-5-8-16-18-19(26(6-2)7-3)23-11-12-27(18)20(24-16)25(4)17-10-9-14(21)13-15(17)22/h9-13H,5-8H2,1-4H3
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PubMed
 324n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.

Bioorg Med Chem Lett 12: 291-4 (2002)


BindingDB Entry DOI: 10.7270/Q22N54H2
More data for this
Ligand-Target Pair