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BDBM50218685 CHEMBL316839

SMILES: CCCN(CCC)c1nccn2c(nc(CCC)c12)N(C)c1ccc(Cl)cc1Cl

InChI Key: InChIKey=YWBPNWTZKONDAO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218685   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50218685
PNG
(CHEMBL316839)
Show SMILES CCCN(CCC)c1nccn2c(nc(CCC)c12)N(C)c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C22H29Cl2N5/c1-5-8-18-20-21(28(12-6-2)13-7-3)25-11-14-29(20)22(26-18)27(4)19-10-9-16(23)15-17(19)24/h9-11,14-15H,5-8,12-13H2,1-4H3
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PubMed
 623n/an/an/an/an/an/an/an/a



DuPont Pharmaceuticals Company

Curated by ChEMBL


Assay Description
Binding affinity at corticotropin releasing hormone receptor in rat frontal cortex homogenates by [125I]Tyr-o-CRF displacement.

Bioorg Med Chem Lett 12: 291-4 (2002)


BindingDB Entry DOI: 10.7270/Q22N54H2
More data for this
Ligand-Target Pair