BDBM50218738 3-(4-hydroxy-3-methoxyphenyl)-5,10-dihydro-11H-dibenzo-[b,e][1,4]diazepin-11-one::3-(4-hydroxy-3-methoxyphenyl)-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one::CHEMBL241966

SMILES: COc1cc(ccc1O)-c1ccc2c(Nc3ccccc3NC2=O)c1

InChI Key: InChIKey=PXOHQDXKTGGDLH-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218738   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50218738 (3-(4-hydroxy-3-methoxyphenyl)-5,10-dihydro-11H-dib...) Show SMILES COc1cc(ccc1O)-c1ccc2c(Nc3ccccc3NC2=O)c1 Show InChI InChI=1S/C20H16N2O3/c1-25-19-11-13(7-9-18(19)23)12-6-8-14-17(10-12)21-15-4-2-3-5-16(15)22-20(14)24/h2-11,21,23H,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Chk1				J Med Chem 52: 3159-65 (2009) Article DOI: 10.1021/jm801444x BindingDB Entry DOI: 10.7270/Q2FF3TM8
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50218738 (3-(4-hydroxy-3-methoxyphenyl)-5,10-dihydro-11H-dib...) Show SMILES COc1cc(ccc1O)-c1ccc2c(Nc3ccccc3NC2=O)c1 Show InChI InChI=1S/C20H16N2O3/c1-25-19-11-13(7-9-18(19)23)12-6-8-14-17(10-12)21-15-4-2-3-5-16(15)22-20(14)24/h2-11,21,23H,1H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human recombinant Chk1				J Med Chem 50: 4162-76 (2007) Article DOI: 10.1021/jm070105d BindingDB Entry DOI: 10.7270/Q22J6BKS
					More data for this Ligand-Target Pair