BDBM50218798 CHEMBL91371
SMILES: Brc1ccc(cc1)-c1ccc(COc2cccc3c2C(=O)C=CC32Oc3cccc4cccc(O2)c34)o1
InChI Key: InChIKey=LQZPOIXLOUHPNF-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thioredoxin reductase 3 (Homo sapiens (Human)) | BDBM50218798 (CHEMBL91371) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 2.01E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of thioredoxin reductase | Bioorg Med Chem Lett 11: 2637-41 (2001) BindingDB Entry DOI: 10.7270/Q22R3TTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thioredoxin reductase 3 (Homo sapiens (Human)) | BDBM50218798 (CHEMBL91371) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Inhibition of thioredoxin-1/thioredoxin reductase system | Bioorg Med Chem Lett 11: 2637-41 (2001) BindingDB Entry DOI: 10.7270/Q22R3TTN | |||||||||||
More data for this Ligand-Target Pair |