BindingDB logo
myBDB logout

null

SMILES: CN(C)C(=O)C(=O)c1c[nH]c2ccc(cc12)C(=O)N1CCc2c(C1)cnn2-c1ccccc1Cl

InChI Key: InChIKey=CTTUJGJIKMIXEI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218823   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50218823
PNG
(2-(5-(1-(2-chlorophenyl)-4,5,6,7-tetrahydro-1H-pyr...)
Show SMILES CN(C)C(=O)C(=O)c1c[nH]c2ccc(cc12)C(=O)N1CCc2c(C1)cnn2-c1ccccc1Cl
Show InChI InChI=1S/C25H22ClN5O3/c1-29(2)25(34)23(32)18-13-27-20-8-7-15(11-17(18)20)24(33)30-10-9-21-16(14-30)12-28-31(21)22-6-4-3-5-19(22)26/h3-8,11-13,27H,9-10,14H2,1-2H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 37n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of p38alpha MAP kinase

Bioorg Med Chem Lett 17: 5019-24 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.029
BindingDB Entry DOI: 10.7270/Q2XW4JHT
More data for this
Ligand-Target Pair