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BDBM50219048 CHEMBL244372::N-(3-{1-[4-(4-chlorophenyl)-4-oxobutyl]-4-piperidinyl}phenyl)-2-phenylacetamide

SMILES: Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)Cc2ccccc2)c1

InChI Key: InChIKey=UIHOENHXMONZDL-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219048   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GPR24


(RAT)
BDBM50219048
PNG
(CHEMBL244372 | N-(3-{1-[4-(4-chlorophenyl)-4-oxobu...)
Show SMILES Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C29H31ClN2O2/c30-26-13-11-24(12-14-26)28(33)10-5-17-32-18-15-23(16-19-32)25-8-4-9-27(21-25)31-29(34)20-22-6-2-1-3-7-22/h1-4,6-9,11-14,21,23H,5,10,15-20H2,(H,31,34)
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
84n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]T226296 from rat recombinant MCH1 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50219048
PNG
(CHEMBL244372 | N-(3-{1-[4-(4-chlorophenyl)-4-oxobu...)
Show SMILES Clc1ccc(cc1)C(=O)CCCN1CCC(CC1)c1cccc(NC(=O)Cc2ccccc2)c1
Show InChI InChI=1S/C29H31ClN2O2/c30-26-13-11-24(12-14-26)28(33)10-5-17-32-18-15-23(16-19-32)25-8-4-9-27(21-25)31-29(34)20-22-6-2-1-3-7-22/h1-4,6-9,11-14,21,23H,5,10,15-20H2,(H,31,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
780n/an/an/an/an/an/an/an/a



Lundbeck Research USA, Inc.

Curated by ChEMBL


Assay Description
Displacement of [3H]spiperone from human recombinant dopamine D2 receptor


J Med Chem 50: 3883-90 (2007)


Article DOI: 10.1021/jm060383x
BindingDB Entry DOI: 10.7270/Q25D8RJM
More data for this
Ligand-Target Pair