BDBM50219057 CHEMBL395789::N-(3-{1-[4-(4-methylphenyl)-4-oxobutyl]-4-piperidinyl}phenyl}-acetamide

SMILES: CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)cc2)CC1

InChI Key: InChIKey=MRSTZRHYYBFJBO-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GPR24 (RAT)	BDBM50219057 (CHEMBL395789 | N-(3-{1-[4-(4-methylphenyl)-4-oxobu...) Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H30N2O2/c1-18-8-10-21(11-9-18)24(28)7-4-14-26-15-12-20(13-16-26)22-5-3-6-23(17-22)25-19(2)27/h3,5-6,8-11,17,20H,4,7,12-16H2,1-2H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]T226296 from rat recombinant MCH1 receptor				J Med Chem 50: 3883-90 (2007) Article DOI: 10.1021/jm060383x BindingDB Entry DOI: 10.7270/Q25D8RJM
					More data for this Ligand-Target Pair
GPR24 (RAT)	BDBM50219057 (CHEMBL395789 | N-(3-{1-[4-(4-methylphenyl)-4-oxobu...) Show SMILES CC(=O)Nc1cccc(c1)C1CCN(CCCC(=O)c2ccc(C)cc2)CC1 Show InChI InChI=1S/C24H30N2O2/c1-18-8-10-21(11-9-18)24(28)7-4-14-26-15-12-20(13-16-26)22-5-3-6-23(17-22)25-19(2)27/h3,5-6,8-11,17,20H,4,7,12-16H2,1-2H3,(H,25,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assay				J Med Chem 50: 3883-90 (2007) Article DOI: 10.1021/jm060383x BindingDB Entry DOI: 10.7270/Q25D8RJM
					More data for this Ligand-Target Pair