BDBM50219164 CHEMBL156893

SMILES: Nc1nccc(n1)-c1ccccc1NCC1=NCCN1

InChI Key: InChIKey=OAHLECZZVVVHND-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50219164 (CHEMBL156893) Show SMILES Nc1nccc(n1)-c1ccccc1NCC1=NCCN1 |t:17| Show InChI InChI=1S/C14H16N6/c15-14-18-6-5-12(20-14)10-3-1-2-4-11(10)19-9-13-16-7-8-17-13/h1-6,19H,7-9H2,(H,16,17)(H2,15,18,20)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	43	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro activation of human alpha-1A receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Alpha adrenergic receptor (1a and 1d) (Homo sapiens (Human))	BDBM50219164 (CHEMBL156893) Show SMILES Nc1nccc(n1)-c1ccccc1NCC1=NCCN1 |t:17| Show InChI InChI=1S/C14H16N6/c15-14-18-6-5-12(20-14)10-3-1-2-4-11(10)19-9-13-16-7-8-17-13/h1-6,19H,7-9H2,(H,16,17)(H2,15,18,20)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	29	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro activation of human alpha-1D receptor expressed in rat-1 fibroblasts via calcium using mobilization through the Gq coupled PLC pathway as fu...				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair
Adrenergic receptor alpha (Homo sapiens (Human))	BDBM50219164 (CHEMBL156893) Show SMILES Nc1nccc(n1)-c1ccccc1NCC1=NCCN1 |t:17| Show InChI InChI=1S/C14H16N6/c15-14-18-6-5-12(20-14)10-3-1-2-4-11(10)19-9-13-16-7-8-17-13/h1-6,19H,7-9H2,(H,16,17)(H2,15,18,20)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	<5.01E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description In vitro activation of human Alpha-1B receptor expressed in rat-1 fibroblasts via calcium mobilization through the Gq coupled PLC pathway as function...				Bioorg Med Chem Lett 12: 575-9 (2002) BindingDB Entry DOI: 10.7270/Q2Z320ZN
					More data for this Ligand-Target Pair