BDBM50219257 6-(3-chloro-4-fluorophenyl)-1-cyclopentyl-1,3-dihydro-2H-benzimidazole-2-thione::CHEMBL241642

SMILES: Fc1ccc(cc1Cl)-c1ccc2[nH]c(=S)n(C3CCCC3)c2c1

InChI Key: InChIKey=FIWISAQRLDBRMJ-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50219257 (6-(3-chloro-4-fluorophenyl)-1-cyclopentyl-1,3-dihy...) Show SMILES Fc1ccc(cc1Cl)-c1ccc2[nH]c(=S)n(C3CCCC3)c2c1 Show InChI InChI=1S/C18H16ClFN2S/c19-14-9-11(5-7-15(14)20)12-6-8-16-17(10-12)22(18(23)21-16)13-3-1-2-4-13/h5-10,13H,1-4H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	49	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assay				Bioorg Med Chem 15: 6556-64 (2007) Article DOI: 10.1016/j.bmc.2007.07.011 BindingDB Entry DOI: 10.7270/Q2CV4HGN
					More data for this Ligand-Target Pair