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BDBM50219313 CHEMBL157812

SMILES: CC(Cn1ccnc1O)c1ccc(OC(F)F)c(OC2CCCC2)c1

InChI Key: InChIKey=LKQUOZFEPAVUHC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219313   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphodiesterase 4 and 5 (PDE4 and PDE5)


(Homo sapiens (Human))		BDBM50219313
PNG
(CHEMBL157812)
Show SMILES CC(Cn1ccnc1O)c1ccc(OC(F)F)c(OC2CCCC2)c1
Show InChI InChI=1S/C18H22F2N2O3/c1-12(11-22-9-8-21-18(22)23)13-6-7-15(25-17(19)20)16(10-13)24-14-4-2-3-5-14/h6-10,12,14,17H,2-5,11H2,1H3,(H,21,23)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a<10n/an/an/an/an/an/a



Janssen-Cilag

Curated by ChEMBL


Assay Description
Inhibitory activity against recombinant phosphodiesterase 4B (PDE4B) of human mononuclear lymphocytes

Bioorg Med Chem Lett 12: 653-8 (2002)


BindingDB Entry DOI: 10.7270/Q2DV1KF6
More data for this
Ligand-Target Pair