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SMILES: COc1ccc2CCCC(c2c1)n1c(Br)nc2c(O)nc(N)nc12

InChI Key: InChIKey=RRLNEPXLPBWKEF-UHFFFAOYSA-N

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219336   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A/cAMP-specific 3',5'-cyclic phosphodiesterase 7B


(Homo sapiens (Human))		BDBM50219336
PNG
(CHEMBL11499)
Show SMILES COc1ccc2CCCC(c2c1)n1c(Br)nc2c(O)nc(N)nc12
Show InChI InChI=1S/C16H16BrN5O2/c1-24-9-6-5-8-3-2-4-11(10(8)7-9)22-13-12(19-15(22)17)14(23)21-16(18)20-13/h5-7,11H,2-4H2,1H3,(H3,18,20,21,23)
PDB

KEGG

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PC cid
PC sid
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Similars
PubMed
n/an/a 4.22E+3n/an/an/an/an/an/a



Celltech R& D

Curated by ChEMBL


Assay Description
Inhibition of human Phosphodiesterase 7 of HUT-78 cells

Bioorg Med Chem Lett 11: 1081-3 (2001)


BindingDB Entry DOI: 10.7270/Q25H7JD0
More data for this
Ligand-Target Pair