BDBM50219403 CB-7432::IDOXIFENE::Idoxifene::SB-223030

SMILES: CC\C(=C(/c1ccc(I)cc1)c1ccc(OCCN2CCCC2)cc1)c1ccccc1

InChI Key: InChIKey=JJKOTMDDZAJTGQ-DQSJHHFOSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50219403 (CB-7432 | IDOXIFENE | Idoxifene | SB-223030) Show SMILES CC\C(=C(/c1ccc(I)cc1)c1ccc(OCCN2CCCC2)cc1)c1ccccc1 Show InChI InChI=1S/C28H30INO/c1-2-27(22-8-4-3-5-9-22)28(23-10-14-25(29)15-11-23)24-12-16-26(17-13-24)31-21-20-30-18-6-7-19-30/h3-5,8-17H,2,6-7,18-21H2,1H3/b28-27-	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibitory activity against calmodulin-dependent Phosphodiesterase was reported.				J Med Chem 39: 999-1004 (1996) Article DOI: 10.1021/jm9505472 BindingDB Entry DOI: 10.7270/Q2JD50HB
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50219403 (CB-7432 | IDOXIFENE | Idoxifene | SB-223030) Show SMILES CC\C(=C(/c1ccc(I)cc1)c1ccc(OCCN2CCCC2)cc1)c1ccccc1 Show InChI InChI=1S/C28H30INO/c1-2-27(22-8-4-3-5-9-22)28(23-10-14-25(29)15-11-23)24-12-16-26(17-13-24)31-21-20-30-18-6-7-19-30/h3-5,8-17H,2,6-7,18-21H2,1H3/b28-27-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Displacement of [3H]17-beta-estradiol from Estrogen receptor of rabbit uterine tissue				Bioorg Med Chem Lett 12: 17-9 (2002) BindingDB Entry DOI: 10.7270/Q2X350NF
					More data for this Ligand-Target Pair