BDBM50219754 1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperazine hydrochloride::CHEMBL536305

SMILES: C(CN1CCN(CC1)C1CCCCC1)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=QMRKWGCOHKOCMS-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50219754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50219754 (1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperaz...) Show SMILES C(CN1CCN(CC1)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C25H33N3/c1-2-9-21(10-3-1)27-19-17-26(18-20-27)15-8-16-28-24-13-6-4-11-22(24)23-12-5-7-14-25(23)28/h4-7,11-14,21H,1-3,8-10,15-20H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong Medical University Curated by ChEMBL					Assay Description Binding affinity to sigma-2 receptor (unknown origin)				Eur J Med Chem 147: 227-237 (2018) Article DOI: 10.1016/j.ejmech.2017.11.016 BindingDB Entry DOI: 10.7270/Q2SQ92XB
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50219754 (1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperaz...) Show SMILES C(CN1CCN(CC1)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C25H33N3/c1-2-9-21(10-3-1)27-19-17-26(18-20-27)15-8-16-28-24-13-6-4-11-22(24)23-12-5-7-14-25(23)28/h4-7,11-14,21H,1-3,8-10,15-20H2	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	79.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]emopamil from Delta-(8)-Delta-(7) sterol isomerase in guinea pig liver membrane				J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50219754 (1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperaz...) Show SMILES C(CN1CCN(CC1)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C25H33N3/c1-2-9-21(10-3-1)27-19-17-26(18-20-27)15-8-16-28-24-13-6-4-11-22(24)23-12-5-7-14-25(23)28/h4-7,11-14,21H,1-3,8-10,15-20H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Guangdong Medical University Curated by ChEMBL					Assay Description Binding affinity to sigma-1 receptor (unknown origin)				Eur J Med Chem 147: 227-237 (2018) Article DOI: 10.1016/j.ejmech.2017.11.016 BindingDB Entry DOI: 10.7270/Q2SQ92XB
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50219754 (1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperaz...) Show SMILES C(CN1CCN(CC1)C1CCCCC1)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C25H33N3/c1-2-9-21(10-3-1)27-19-17-26(18-20-27)15-8-16-28-24-13-6-4-11-22(24)23-12-5-7-14-25(23)28/h4-7,11-14,21H,1-3,8-10,15-20H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Displacement of [3H]pentazocine from Sigma1 receptor in guinea pig brain membrane				J Med Chem 50: 4648-55 (2007) Article DOI: 10.1021/jm070373b BindingDB Entry DOI: 10.7270/Q2SQ917Z
					More data for this Ligand-Target Pair