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SMILES: Fc1ccc(NC(=O)c2ccc(OCC(=O)Nc3cccc(Br)c3)nc2)cc1

InChI Key: InChIKey=HKTTWGQIGMESRW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219801   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-X-C chemokine receptor type 1/2


(Homo sapiens (Human))		BDBM50219801
PNG
(CHEMBL40558)
Show SMILES Fc1ccc(NC(=O)c2ccc(OCC(=O)Nc3cccc(Br)c3)nc2)cc1
Show InChI InChI=1S/C20H15BrFN3O3/c21-14-2-1-3-17(10-14)24-18(26)12-28-19-9-4-13(11-23-19)20(27)25-16-7-5-15(22)6-8-16/h1-11H,12H2,(H,24,26)(H,25,27)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 2.70E+3n/an/an/an/an/an/a



Celltech R&D Inc.

Curated by ChEMBL


Assay Description
Inhibition against GRO-alpha driven human neutrophil chemotaxis

Bioorg Med Chem Lett 12: 1517-20 (2002)


BindingDB Entry DOI: 10.7270/Q2JM28ZD
More data for this
Ligand-Target Pair