BDBM50219817 CHEMBL43607

SMILES: COc1ccc(C(=O)Nc2ccncc2Cl)c2cccnc12

InChI Key: InChIKey=JCDIHRDMTWMTBI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50219817 (CHEMBL43607) Show SMILES COc1ccc(C(=O)Nc2ccncc2Cl)c2cccnc12 Show InChI InChI=1S/C16H12ClN3O2/c1-22-14-5-4-11(10-3-2-7-19-15(10)14)16(21)20-13-6-8-18-9-12(13)17/h2-9H,1H3,(H,18,20,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Celltech R&D Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 4 (PDE-4) from human U937 cells				Bioorg Med Chem Lett 12: 1613-5 (2002) BindingDB Entry DOI: 10.7270/Q2D220S3
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4C (Rattus norvegicus)	BDBM50219817 (CHEMBL43607) Show SMILES COc1ccc(C(=O)Nc2ccncc2Cl)c2cccnc12 Show InChI InChI=1S/C16H12ClN3O2/c1-22-14-5-4-11(10-3-2-7-19-15(10)14)16(21)20-13-6-8-18-9-12(13)17/h2-9H,1H3,(H,18,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Celltech R&D Curated by ChEMBL					Assay Description Inhibition of rolipram binding in rat brain				Bioorg Med Chem Lett 12: 1613-5 (2002) BindingDB Entry DOI: 10.7270/Q2D220S3
					More data for this Ligand-Target Pair