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SMILES: NS(=O)(=O)Cc1ccc(cc1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=HCLDSBXOHDDBRK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220174   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50220174
PNG
(1-[4'-(trifluoromethyl)-4-biphenylyl]methanesulfon...)
Show SMILES NS(=O)(=O)Cc1ccc(cc1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C14H12F3NO2S/c15-14(16,17)13-7-5-12(6-8-13)11-3-1-10(2-4-11)9-21(18,19)20/h1-8H,9H2,(H2,18,19,20)
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Similars
Article
PubMed
n/an/a 118n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human KSP motor domain by ATPase assay

J Med Chem 50: 4939-52 (2007)


Article DOI: 10.1021/jm070435y
BindingDB Entry DOI: 10.7270/Q29023H4
More data for this
Ligand-Target Pair