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SMILES: NS(=O)(=O)Nc1ccc(cc1)-c1ccc2OC(F)(F)C(F)(F)Oc2c1

InChI Key: InChIKey=NPKDGTGKGPCJNS-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220181   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50220181
PNG
(CHEMBL397673 | N-[4-(2,2,3,3-tetrafluoro-2,3-dihyd...)
Show SMILES NS(=O)(=O)Nc1ccc(cc1)-c1ccc2OC(F)(F)C(F)(F)Oc2c1
Show InChI InChI=1S/C14H10F4N2O4S/c15-13(16)14(17,18)24-12-7-9(3-6-11(12)23-13)8-1-4-10(5-2-8)20-25(19,21)22/h1-7,20H,(H2,19,21,22)
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n/an/a 67n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human KSP motor domain by ATPase assay

J Med Chem 50: 4939-52 (2007)


Article DOI: 10.1021/jm070435y
BindingDB Entry DOI: 10.7270/Q29023H4
More data for this
Ligand-Target Pair