BDBM50220201 CHEMBL243431::N-[3-amino-4'-(trifluoromethyl)-4-biphenylyl]sulfamide

SMILES: Nc1cc(ccc1NS(N)(=O)=O)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=BPJTUAGUVDDBHV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein 1 (Homo sapiens (Human))	BDBM50220201 (CHEMBL243431 | N-[3-amino-4'-(trifluoromethyl)-4-b...) Show SMILES Nc1cc(ccc1NS(N)(=O)=O)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C13H12F3N3O2S/c14-13(15,16)10-4-1-8(2-5-10)9-3-6-12(11(17)7-9)19-22(18,20)21/h1-7,19H,17H2,(H2,18,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human KSP motor domain by ATPase assay				J Med Chem 50: 4939-52 (2007) Article DOI: 10.1021/jm070435y BindingDB Entry DOI: 10.7270/Q29023H4
					More data for this Ligand-Target Pair