BDBM50220317 CHEMBL236850::N-(diaminomethylene)-2-(2,4-diphenylthiophen-3-yl)acetamide

SMILES: NC(=N)NC(=O)Cc1c(csc1-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=PPKBHBJOIMCNRC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220317   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM50220317 (CHEMBL236850 | N-(diaminomethylene)-2-(2,4-dipheny...) Show SMILES NC(=N)NC(=O)Cc1c(csc1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C19H17N3OS/c20-19(21)22-17(23)11-15-16(13-7-3-1-4-8-13)12-24-18(15)14-9-5-2-6-10-14/h1-10,12H,11H2,(H4,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of BACE1 by FRET assay				Bioorg Med Chem Lett 17: 5353-6 (2007) Article DOI: 10.1016/j.bmcl.2007.08.010 BindingDB Entry DOI: 10.7270/Q2WQ03GF
					More data for this Ligand-Target Pair