BDBM50220383 4'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitrile::CHEMBL235159

SMILES: COc1ccc(cc1)-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key: InChIKey=STNCCUKDFSTRBR-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50220383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50220383 (4'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...) Show SMILES COc1ccc(cc1)-c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C15H10F3NO/c1-20-13-6-4-10(5-7-13)11-2-3-12(9-19)14(8-11)15(16,17)18/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56.7	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cells				Bioorg Med Chem Lett 17: 5529-32 (2007) Article DOI: 10.1016/j.bmcl.2007.08.034 BindingDB Entry DOI: 10.7270/Q2CR5T3S
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50220383 (4'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...) Show SMILES COc1ccc(cc1)-c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C15H10F3NO/c1-20-13-6-4-10(5-7-13)11-2-3-12(9-19)14(8-11)15(16,17)18/h2-8H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assay				Bioorg Med Chem Lett 17: 5529-32 (2007) Article DOI: 10.1016/j.bmcl.2007.08.034 BindingDB Entry DOI: 10.7270/Q2CR5T3S
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50220383 (4'-methoxy-3-trifluoromethyl-biphenyl-4-carbonitri...) Show SMILES COc1ccc(cc1)-c1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C15H10F3NO/c1-20-13-6-4-10(5-7-13)11-2-3-12(9-19)14(8-11)15(16,17)18/h2-8H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity at human PR				Bioorg Med Chem Lett 17: 5529-32 (2007) Article DOI: 10.1016/j.bmcl.2007.08.034 BindingDB Entry DOI: 10.7270/Q2CR5T3S
					More data for this Ligand-Target Pair