Found 3 hits for monomerid = 50220411 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50220411
(CHEMBL291882)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2sccc2Cl)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-3-4-6-22(28)19-7-9-20(10-8-19)30-17-5-12-26-13-15-27(16-14-26)24(29)23-21(25)11-18-31-23/h7-11,18H,2-6,12-17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for the rat cortical Histamine H3 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this Ligand-Target Pair | |
Histamine H1 receptor
(Homo sapiens (Human)) | BDBM50220411
(CHEMBL291882)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2sccc2Cl)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-3-4-6-22(28)19-7-9-20(10-8-19)30-17-5-12-26-13-15-27(16-14-26)24(29)23-21(25)11-18-31-23/h7-11,18H,2-6,12-17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for the human Histamine H1 Receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this Ligand-Target Pair | |
Histamine H2 receptor
(Homo sapiens (Human)) | BDBM50220411
(CHEMBL291882)Show SMILES CCCCCC(=O)c1ccc(OCCCN2CCN(CC2)C(=O)c2sccc2Cl)cc1 Show InChI InChI=1S/C24H31ClN2O3S/c1-2-3-4-6-22(28)19-7-9-20(10-8-19)30-17-5-12-26-13-15-27(16-14-26)24(29)23-21(25)11-18-31-23/h7-11,18H,2-6,12-17H2,1H3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Binding affinity for the human Histamine H2 receptor |
Bioorg Med Chem Lett 12: 2031-4 (2002)
BindingDB Entry DOI: 10.7270/Q2MK6G21 |
More data for this Ligand-Target Pair | |