BindingDB logo
myBDB logout

BDBM50220487 CHEMBL26347

SMILES: CCCC(C)n1c(CC)nc2c(nccc12)-c1ccc(cc1Cl)C(F)(F)F

InChI Key: InChIKey=CEXYUPVEQPPUHE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220487   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor


(Rattus norvegicus (rat)-RAT)		BDBM50220487
PNG
(CHEMBL26347)
Show SMILES CCCC(C)n1c(CC)nc2c(nccc12)-c1ccc(cc1Cl)C(F)(F)F
Show InChI InChI=1S/C20H21ClF3N3/c1-4-6-12(3)27-16-9-10-25-18(19(16)26-17(27)5-2)14-8-7-13(11-15(14)21)20(22,23)24/h7-12H,4-6H2,1-3H3
PDB
MMDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 3.5n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
In vitro binding affinity against Corticotropin releasing factor receptor in rat cortical homogenates

Bioorg Med Chem Lett 13: 129-31 (2003)


BindingDB Entry DOI: 10.7270/Q2DZ0BGD
More data for this
Ligand-Target Pair