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BDBM50220488 CHEMBL447475

SMILES: CCC(C)n1c(CC)nc2c(nccc12)-c1ccc(OC(F)(F)F)cc1Cl

InChI Key: InChIKey=DSQYKFOBHXWQAX-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220488   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin-releasing factor receptor 1/2


(Rattus norvegicus (rat)-RAT)		BDBM50220488
PNG
(CHEMBL447475)
Show SMILES CCC(C)n1c(CC)nc2c(nccc12)-c1ccc(OC(F)(F)F)cc1Cl
Show InChI InChI=1S/C19H19ClF3N3O/c1-4-11(3)26-15-8-9-24-17(18(15)25-16(26)5-2)13-7-6-12(10-14(13)20)27-19(21,22)23/h6-11H,4-5H2,1-3H3
PDB
MMDB

UniProtKB/SwissProt

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AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 7.80n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
In vitro binding affinity against CRF receptor in rat cortical homogenates

Bioorg Med Chem Lett 13: 129-31 (2003)


BindingDB Entry DOI: 10.7270/Q2DZ0BGD
More data for this
Ligand-Target Pair