BDBM50220713 CHEMBL237323::N-((1r,4r)-4-(4-hydroxy-2-methylphenyl)cyclohexyl)-3-phenylpropanamide

SMILES: Cc1cc(O)ccc1[C@H]1CC[C@@H](CC1)NC(=O)CCc1ccccc1

InChI Key: InChIKey=WHIWOTLPHYDESG-WGSAOQKQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220713   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50220713 (CHEMBL237323 | N-((1r,4r)-4-(4-hydroxy-2-methylphe...) Show SMILES Cc1cc(O)ccc1[C@H]1CC[C@@H](CC1)NC(=O)CCc1ccccc1 |wU:8.8,wD:11.15,(-7.33,-40.77,;-7.32,-42.31,;-8.64,-43.08,;-8.65,-44.63,;-9.97,-45.4,;-7.3,-45.4,;-5.97,-44.62,;-5.99,-43.08,;-4.65,-42.31,;-4.65,-40.77,;-3.32,-39.98,;-1.98,-40.77,;-1.98,-42.31,;-3.32,-43.08,;-.65,-40,;.69,-40.77,;.69,-42.32,;2.03,-40.01,;3.35,-40.79,;4.69,-40.03,;6.01,-40.81,;7.36,-40.05,;7.36,-38.51,;6.04,-37.73,;4.71,-38.49,)| Show InChI InChI=1S/C22H27NO2/c1-16-15-20(24)12-13-21(16)18-8-10-19(11-9-18)23-22(25)14-7-17-5-3-2-4-6-17/h2-6,12-13,15,18-19,24H,7-11,14H2,1H3,(H,23,25)/t18-,19-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	722	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]CP101,606 from NR2B in rat forebrain P2 membrane				Bioorg Med Chem Lett 17: 5533-6 (2007) Article DOI: 10.1016/j.bmcl.2007.08.039 BindingDB Entry DOI: 10.7270/Q23778FR
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50220713 (CHEMBL237323 | N-((1r,4r)-4-(4-hydroxy-2-methylphe...) Show SMILES Cc1cc(O)ccc1[C@H]1CC[C@@H](CC1)NC(=O)CCc1ccccc1 |wU:8.8,wD:11.15,(-7.33,-40.77,;-7.32,-42.31,;-8.64,-43.08,;-8.65,-44.63,;-9.97,-45.4,;-7.3,-45.4,;-5.97,-44.62,;-5.99,-43.08,;-4.65,-42.31,;-4.65,-40.77,;-3.32,-39.98,;-1.98,-40.77,;-1.98,-42.31,;-3.32,-43.08,;-.65,-40,;.69,-40.77,;.69,-42.32,;2.03,-40.01,;3.35,-40.79,;4.69,-40.03,;6.01,-40.81,;7.36,-40.05,;7.36,-38.51,;6.04,-37.73,;4.71,-38.49,)| Show InChI InChI=1S/C22H27NO2/c1-16-15-20(24)12-13-21(16)18-8-10-19(11-9-18)23-22(25)14-7-17-5-3-2-4-6-17/h2-6,12-13,15,18-19,24H,7-11,14H2,1H3,(H,23,25)/t18-,19-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human HERG expressed in HEK293 cells				Bioorg Med Chem Lett 17: 5533-6 (2007) Article DOI: 10.1016/j.bmcl.2007.08.039 BindingDB Entry DOI: 10.7270/Q23778FR
					More data for this Ligand-Target Pair