BDBM50220731 CHEMBL393609::N-((1r,4r)-4-(4-hydroxyphenyl)cyclohexyl)-3-(1-methyl-1H-benzo[d]imidazol-2-yl)propanamide

SMILES: Cn1c(CCC(=O)N[C@H]2CC[C@@H](CC2)c2ccc(O)cc2)nc2ccccc12

InChI Key: InChIKey=QPAULAIWIRXKJN-SAABIXHNSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50220731 (CHEMBL393609 | N-((1r,4r)-4-(4-hydroxyphenyl)cyclo...) Show SMILES Cn1c(CCC(=O)N[C@H]2CC[C@@H](CC2)c2ccc(O)cc2)nc2ccccc12 |wU:11.14,wD:8.7,(27.83,-9.24,;27.07,-7.91,;25.61,-7.43,;24.27,-8.19,;22.94,-7.41,;21.6,-8.17,;21.6,-9.72,;20.26,-7.4,;18.93,-8.17,;17.58,-7.38,;16.25,-8.17,;16.25,-9.71,;17.58,-10.48,;18.93,-9.71,;14.92,-10.49,;13.58,-9.71,;12.24,-10.49,;12.24,-12.04,;10.91,-12.81,;13.59,-12.8,;14.93,-12.03,;25.61,-5.89,;27.08,-5.42,;27.84,-3.92,;29.37,-3.9,;30.15,-5.23,;29.39,-6.56,;27.85,-6.57,)| Show InChI InChI=1S/C23H27N3O2/c1-26-21-5-3-2-4-20(21)25-22(26)14-15-23(28)24-18-10-6-16(7-11-18)17-8-12-19(27)13-9-17/h2-5,8-9,12-13,16,18,27H,6-7,10-11,14-15H2,1H3,(H,24,28)/t16-,18-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]CP101,606 from NR2B in rat forebrain P2 membrane				Bioorg Med Chem Lett 17: 5533-6 (2007) Article DOI: 10.1016/j.bmcl.2007.08.039 BindingDB Entry DOI: 10.7270/Q23778FR
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